Explanation: Here, you’re asked about the interactions between Persia and Arabia in the period 600 to 1450 (C) E. Historically, the armies of Islam, starting in Arabia, overran the Sassanid Empire around 650 (C) E., so find the choice that matches best with this idea. Choice (A) references the idea that Persia conquered Arabia, which is the opposite of what you’re looking for, so eliminate (A). Choice (B), the idea that the two nations did not interact with each other, is not true, so eliminate (B). Choice (C), the idea that the Persians supported Arab client states, is true for the period 600 (B) (C) E.–600 (C) E.; this is not the correct period, so eliminate (C). Choice (D), which states Persia was overrun by Arabia, is true, so keep it. The correct answer is (D).